Maybe you have long been familiar with mefenamic acid, ibuprofen, diclofenac or aspirin (there are many more kinds of other things). All drug classes that include pain relievers or more popular known as analgesics. Pain is the body’s response to an “irregularity” in our bodies, whether they are normal (physiological) or abnormal (pathological), in other words the pain can be regarded as “ALARM” of our body that something is “wrong” in the our bodies. As technological developments, have now known some “triggers” the emergence of pain. A process of inflammation, whether due to infection or trauma are considered as conditions that may cause pain. A number of chemical substances in the process of inflammation is a strong role in the process of pain. Prostaglandins, is one of the most popular pain mediators. This substance stimulates pain receptors and stimulate nerve endings and then through a number of processes delivered to the brain until then the perception of pain occurs. All analgesics are classified in the non-steroidal anti-inflammatory (analgesic of this type most widely circulated in the community) work by inhibiting prostaglandin production in a series of inflammatory processes (inflammation), so with no formation of prostaglandins it will not happen on the stimulation of pain receptors on the tips of nerve endings that will culminate in the disappearance of pain. But this is not entirely favorable conditions for our bodies, because Prostaglandins are also required for normal processes in the body such as blood clotting process and the process of our digestive tract system maintenance. Please note that our digestive tract is one organ that potentially cause major problems for ourselves. You can imagine how our stomachs able to “survive” against a very strong stomach acid? Gastric acid has a degree of acidity (pH) to range from 0.7 to 3.8 that is able to make the metal damaged by the corrosive nature of the acid ..!